Basics of Receptor Pharmacology 🩺

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#drnajeeb #medicaleducation #medicines #pharmacology #receptores #receptores • Basics of Receptor | Pharmacology 🩺 • Like this video? • Sign up now on our website at https://www.DrNajeebLectures.com to access 1000+ Exclusive videos on Basic Medical Sciences Clinical Medicine. These are premium videos (NOT FROM YOUTUBE). All these videos come with English subtitles download options. Sign up now! Get Lifetime Access for a one-time payment of $59 ONLY! • Sign up now on our website at https://members.drnajeeblectures.com/ • --------------------------------------------------------------------------------------------------------------------------- • Why sign up for premium membership? Here's why! • Membership Features for premium website members. • 1. More than 1000+ Medical Lectures. • 2. Basic Medical Sciences Clinical Medicine. • 3. Mobile-friendly interface with android and iOS apps. • 4. English subtitles and new videos every week. • 5. Download option for offline video playback. • 6. Fanatic customer support and that's 24/7. • 7. Fast video playback option to learn faster. • 8. Trusted by over 2M+ students in 190 countries. • --------------------------------------------------------------------------------------------------------------------------- • ▬▬▬▬▬▬▬▬▬▬ Contents of this video ▬▬▬▬▬▬▬▬▬▬ • 00:00:00 What Is Receptor? • 00:00:46 What Is DNA? • 00:01:38 Functions Of Receptors • 00:02:20 Ligand Binding Domain • 00:03:45 Effector Domain • 00:05:03 Review • 00:05:40 Plasma Proteins • 00:08:38 Question About Biologiocal Response • --------------------------------------------------------------------------------------------------------------------------- • In biochemistry and pharmacology, receptors are chemical structures, composed of protein, that receive and transduce signals that may be integrated into biological systems. These signals are typically chemical messengers[nb 1] which bind to a receptor and produce physiological responses such as change in the electrical activity of a cell. For example, GABA, an inhibitory neurotransmitter inhibits electrical activity of neurons by binding to GABAA receptors. There are three main ways the action of the receptor can be classified: relay of signal, amplification, or integration. Relaying sends the signal onward, amplification increases the effect of a single ligand, and integration allows the signal to be incorporated into another biochemical pathway. • Receptor proteins can be classified by their location. Cell surface receptors also known as transmembrane receptors, include ligand-gated ion channels, G protein-coupled receptors, and enzyme-linked hormone receptors. Intracellular receptors are those found inside the cell, and include cytoplasmic receptors and nuclear receptors. A molecule that binds to a receptor is called a ligand and can be a protein, peptide (short protein), or another small molecule, such as a neurotransmitter, hormone, pharmaceutical drug, toxin, calcium ion or parts of the outside of a virus or microbe. An endogenously produced substance that binds to a particular receptor is referred to as its endogenous ligand. E.g. the endogenous ligand for the nicotinic acetylcholine receptor is acetylcholine, but it can also be activated by nicotine and blocked by curare. Receptors of a particular type are linked to specific cellular biochemical pathways that correspond to the signal. While numerous receptors are found in most cells, each receptor will only bind with ligands of a particular structure. This has been analogously compared to how locks will only accept specifically shaped keys. When a ligand binds to a corresponding receptor, it activates or inhibits the receptor's associated biochemical pathway, which may also be highly specialised. • --------------------------------------------------------------------------------------------------------------------------- • Join this channel to get access to the perks: • Sign up now on our website at https://members.drnajeeblectures.com/ • Follow us on Facebook:- / drnajeeb • Follow us on Instagram:- / drnajeeblectures

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