糖尿病腎病變治療藥物新進展

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DKD是一種嚴重且常見的糖尿病併發症，對患者的預後有重大影響。透過控制血糖、血壓和血脂，以及使用有效的藥物治療，可以顯著延緩病程進展。目前已有多種藥物在DKD的治療中顯示出良好的效果。藉由這些新進展，我們對於DKD的治療將有更多的選擇和希望，進一步改善患者的生活品質和長期預後。 • 作者：林奕瑱藥師（社團法人台灣家庭藥師學會） • 台灣家庭藥師學會官網: https://familypharm.org/ • 台灣家庭藥師學會臉書: / profile.php id=100067147454610 mibextid=LQQJ4d • 文獻來源: • 1. Wang JS, Yen FS, Lin KD, Shin SJ, Hsu YH, Hsu CC; Diabetes Kidney Disease Research Committee of the Diabetes Association of the Republic of China (Taiwan). Epidemiological characteristics of diabetic kidney disease in Taiwan. J Diabetes Investig. 2021 Dec;12(12):2112-2123. doi: 10.1111/jdi.13668. Epub 2021 Oct 3. PMID: 34529360; PMCID: PMC8668071. • 2. Nikolaus Marx, Massimo Federici, Katharina Schütt, Dirk Müller-Wieland, Ramzi A Ajjan, Manuel J Antunes, Ruxandra M Christodorescu, Carolyn Crawford, Emanuele Di Angelantonio, Björn Eliasson, Christine Espinola-Klein, Laurent Fauchier, Martin Halle, William G Herrington, Alexandra Kautzky-Willer, Ekaterini Lambrinou, Maciej Lesiak, Maddalena Lettino, Darren K McGuire, Wilfried Mullens, Bianca Rocca, Naveed Sattar, ESC Scientific Document Group , 2023 ESC Guidelines for the management of cardiovascular disease in patients with diabetes: Developed by the task force on the management of cardiovascular disease in patients with diabetes of the European Society of Cardiology (ESC), European Heart Journal, Volume 44, Issue 39, 14 October 2023, Pages 4043–4140, https://doi.org/10.1093/eurheartj/eha... • 3. Di Lullo L, Lavalle C, Scatena A, Mariani MV, Ronco C, Bellasi A. Finerenone: Questions and Answers-The Four Fundamental Arguments on the New-Born Promising Non-Steroidal Mineralocorticoid Receptor Antagonist. J Clin Med. 2023 Jun 12;12(12):3992. doi: 10.3390/jcm12123992. PMID: 37373685; PMCID: PMC10299719. • 4. Kidney Disease: Improving Global Outcomes (KDIGO) Diabetes Work Group. KDIGO 2022 Clinical Practice Guideline for Diabetes Management in Chronic Kidney Disease. Kidney Int. 2022 Nov;102(5S):S1-S127. doi: 10.1016/j.kint.2022.06.008. PMID: 36272764. • 5. Perkovic V, Tuttle KR, Rossing P, Mahaffey KW, Mann JFE, Bakris G, Baeres FMM, Idorn T, Bosch-Traberg H, Lausvig NL, Pratley R; FLOW Trial Committees and Investigators. Effects of Semaglutide on Chronic Kidney Disease in Patients with Type 2 Diabetes. N Engl J Med. 2024 May 24. doi: 10.1056/NEJMoa2403347. Epub ahead of print. PMID: 38785209.

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