βactin mRNA Dynamics in a Migrating Cell

############################# Video Source: www.youtube.com/watch?v=du_iDp_tV5Y

Asymmetric distribution of mRNA is observed in diverse cell types and considered to be an important mechanism to generate cell polarity. Localization of mRNA allows protein synthesis to be regulated at high spatial and temporal resolution. Live-cell imaging reveals that β-actin mRNA localization is highly dynamic and correlated with the cell protrusion and migration. • Real-time dynamics of β-actin mRNA in a migrating cell. The MS2-GFP labeling technique was used to visualize the endogenous β-actin mRNA. The color map shows the fluorescence intensity of NLS-MCP-GFP divided by the intensity of cytoplasmic dye, representing the concentration of β-actin mRNA. • Video courtesy of Hye Yoon Park and Robert H. Singer, Albert Einstein College of Medicine. • See more RNA images in the Cell Picture Show: https://www.cell.com/pictureshow/RNA

#############################

New on site