Apoptosis













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Apoptosis, also known as programmed cell death, is a fundamental biological process that plays a crucial role in maintaining tissue homeostasis, development, and defence mechanisms in multicellular organisms. It is a highly regulated process that eliminates unwanted or damaged cells without causing inflammation or harm to neighbouring cells. Apoptosis is involved in various physiological events, including embryogenesis, organ development, immune response, and the removal of potentially harmful or aged cells. • At the cellular level, apoptosis is characterized by a series of tightly controlled molecular events. The process involves the activation of a cascade of signalling pathways that ultimately lead to cell death. Key players in apoptosis include proteins such as caspases, which act as the executioners of the process. Caspases are responsible for dismantling the cellular components and triggering cell fragmentation. Apoptosis can be initiated through intrinsic or extrinsic pathways. The intrinsic pathway is activated by cellular stressors, such as DNA damage or lack of survival signals, which lead to the release of mitochondrial proteins and subsequent caspase activation. The extrinsic pathway, on the other hand, is initiated by external signals, such as binding of specific molecules to death receptors on the cell surface, triggering the activation of caspases and cell death. • Apoptosis serves as a critical mechanism for maintaining tissue integrity and eliminating cells that could potentially disrupt normal cellular functions. Dysregulation of apoptosis can have severe consequences, leading to various diseases, including cancer, autoimmune disorders, and neurodegenerative conditions. Understanding the intricacies of apoptosis and its underlying molecular mechanisms is essential for gaining insights into both normal development and pathological conditions, offering potential avenues for therapeutic interventions aimed at modulating this intricate cellular process. • Animation By: Sandeep V. Prajapati • Audio By: Kaijin Ruh • ©️ Copyright: Sandbooks Sandeep • If you want and make your customized scientific illustrations, then contact us! • Website: www.sandbooks.in • Email: [email protected] • #animation #apoptosis #cellbiology #biology #immunology #biotechnology #microbiology #sandbooks #illustration • #sandbooksillustrations #sciart #medart #biologicalanimation #scientificanimation • #science #medicalillustration

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