NOD2 Effect on Crohn’s Disease

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In this video I describe what NOD 2 does and how mutations affect the body and causes Crohn’s dz. • #crohnsdisease #dreldersanatomychannel #gastroenterology #medicalpathology • Research I used • NOD2 mutation can lead to alternative pathway • https://pmc.ncbi.nlm.nih.gov/articles.... • • Cytokines released in the alternate pathway • https://www.frontiersin.org/journals/... • Toll like receptors activate NLRP3 inflammosome in crohns • https://pubmed.ncbi.nlm.nih.gov/2509/ • Toll like receptors are on cell membranes of macrophages and epithelial cells • https://pmc.ncbi.nlm.nih.gov/articles.... • • Role of NOD2 and ATG16L1 • https://www.dovepress.com/nod2-and-in...

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