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For the diagnosis of type 1 neurofibromatosis, two or more of the following clinical features must be present: • Six or more café-au-lait macules; in prepubertal children each macule must be more than 5 mm in greatest diameter, while in postpubertal 15 mm is the cut-off • Two or more neurofibromas of any type or one plexiform neurofibroma • Two or more Lisch nodules, which are Iris hamartomas. • Freckling in the axillary or inguinal regions • Optic glioma • Distinctive bony lesion • A first-degree relative with NF1 based upon the above criteria • Music: https://www.bensound.com • 📺 Subscribe To My Channel and Get More Great Quizzes and Tutorials • / @med4vl • #FOAMped #MedEd #pediatrics • Disclaimer: All the information provided by Medical Education for Visual Learners and associated videos are strictly for informational purposes only. It is not intended as a substitute for medical advice from your health care provider or physician. It should not be used to overrule the advice of a qualified healthcare provider, nor to provide advice for emergency medical treatment. If you think that you or someone that you know may be suffering from a medical condition, then please consult your physician or seek immediate medical attention.
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