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Birch Reduction
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http://youtube.com/watch?v=6xg_ijMOso4
The Birch Reduction is an organic chemical reaction that reduces aromatic rings to produce 1,4-cyclohexadienes. Named after Australian chemist Arthur Birch, this reaction involves treating aromatic compounds with a solution of alkali metals (usually sodium or lithium) in liquid ammonia, often with an alcohol as a proton source. The reaction typically converts benzene and other aromatic compounds into less aromatic, partially reduced structures. Commonly used in synthetic organic chemistry, it is a key method for modifying aromatic rings in natural products and pharmaceuticals, as the reduced structures can serve as valuable intermediates for further functionalization. • #snsinstitutions • #snsdesignthinkers • #designthinking • #snscphs
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