Histological Differences between Major salivary Glands parotid submandibular Sublingual











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The three major salivary glands (parotid, submandibular, and sublingual) exhibit distinct histological features: • • Parotid Gland • • 1. Serous secretion • 2. Acinar cells with eosinophilic granules • 3. Ductal system: striated ducts, intercalated ducts, and excretory ducts • 4. Admixed lymphoid tissue (intralobular and extralobular) • 5. Fat cells scattered throughout • • Submandibular Gland • • 1. Mixed serous and mucinous secretion • 2. Acinar cells with both eosinophilic and basophilic granules • 3. Ductal system: striated ducts, intercalated ducts, and excretory ducts • 4. Larger ducts with more prominent smooth muscle • 5. Less lymphoid tissue compared to parotid gland • • Sublingual Gland • • 1. Mucinous secretion • 2. Acinar cells with basophilic granules • 3. Ductal system: primarily intercalated ducts and excretory ducts • 4. Fewer striated ducts • 5. More compact, smaller lobules • • Key Histological Features: • • 1. Acinar cell morphology • 2. Ductal system complexity • 3. Secretion type (serous, mucinous, or mixed) • 4. Lymphoid tissue presence and distribution • 5. Fat cell distribution • • #salivaryglands

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