chromosomal anomalies 2021











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Definition: • A chromosomal anomaly or aberration is a deviation from the normal number or from the normal morphology (shape) of chromosomes. • Chromosomal aberrations may be: • 1- Numerical Aberration: Abnormality in the number of chromosomes. • 2- Structural aberration: Abnormality in the shape of chromosomes. • Both abnormalities may affect autosomes or sex chromosomes. • Causes of Chromosomal Aberrations: • 1- Radiation. • 2- Infection with German measles. • 3- Pregnancy in old age. • 4- Auto-immune diseases. • 5- Family history of chromosomal abnormalities. • chromosomal anomalies • A) Numericall • 1) Sex chromosomes • Male : Klinefelter’s syndrome and YY syndrome • Female: Turner’s syndrome and Multiple x syndrome • 2) Autosomes • B) Structural • 1) deletion: Wolf syndrome and Cri du chat • 2) translocation: Philadelphia ch. • for contact • [email protected] • Telegram channel • https://t.me/drshereenhamed​ • Telegram chat group • https://t.me/joinchat/QU7iQhPd6e8U62f​...

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