Youtor
Pentose Phosphate Pathway Hexose Monophosphate Shunt
>> YOUR LINK HERE: ___ http://youtube.com/watch?v=BXSuqyHlBxk
GLYCOLYSIS PATHWAY : • • Glycolysis Pathway • The pentose phosphate pathway (also called the phosphogluconate pathway and the hexose monophosphate shuntand the HMP Shunt) is a metabolic pathway parallel to glycolysis.[1] It generates NADPH and pentoses (5-carbon sugars) as well as ribose 5-phosphate, a precursor for the synthesis of nucleotides.[2] While the pentose phosphate pathway does involve oxidation of glucose, its primary role is anabolic rather than catabolic. The pathway is especially important in red blood cells (erythrocytes). • There are two distinct phases in the pathway. The first is the oxidative phase, in which NADPH is generated, and the second is the non-oxidative synthesis of 5-carbon sugars. For most organisms, the pentose phosphate pathway takes place in the cytosol; in plants, most steps take place in plastids. • The primary results of the pathway are: • The generation of reducing equivalents, in the form of NADPH, used in reductive biosynthesis reactions within cells (e.g. fatty acid synthesis). • Production of ribose 5-phosphate (R5P), used in the synthesis of nucleotides and nucleic acids. • Production of erythrose 4-phosphate (E4P) used in the synthesis of aromatic amino acids.
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