ICV Injection of Brain for Neuronal Transduction Protocol Preview











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Watch the Full Video at https://www.jove.com/v/51863/intracer.... • Intracerebroventricular Viral Injection of the Neonatal Mouse Brain for Persistent and Widespread Neuronal Transduction - a 2 minute Preview of the Experimental Protocol • Ji-Yoen Kim, Stacy D. Grunke, Yona Levites, Todd E. Golde, Joanna L. Jankowsky • Baylor College of Medicine, Department of Neuroscience; University of Florida, Department of Neuroscience, Center for Translational Research in Neurodegenerative Disease; Baylor College of Medicine, Department of Neurology and Department of Neurosurgery; • Here we demonstrate a technique for widespread neuronal transduction by intraventricular injection of adeno-associated virus into the neonatal mouse brain. This method provides a rapid and easy way to attain lifelong expression of virally-delivered transgenes. • Visit https://www.jove.com?utm_source=youtube utm_medium=social_global utm_campaign=reseach-videos-2022 to explore our entire library of 14,000+ videos of laboratory methods and science concepts. • JoVE is the world-leading producer and provider of science videos with the mission to improve scientific research and education. Millions of scientists, educators, and students at 1500+ institutions worldwide, including schools like Harvard, MIT and Stanford benefit from using JoVE's extensive library of 14,000+ videos in their research,education and teaching. • Subscribe to our channel:    / jovejournalofvisualizedexperiments  

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