Laboratory Synthesis of Aspirin

>> YOUR LINK HERE: ___ http://youtube.com/watch?v=E61AdIYEBuk

Now that we understand the basics regarding NSAIDs, let's dive into a few specific drugs from this class. First up, aspirin. This drug has been around for centuries, but now with a modern understanding of chemistry and biochemistry, we are able to understand its precise structure and mechanism of action. Aspirin is unique among NSAIDs because it covalently alters a serine residue in the active site of cyclooxygenase enzymes, thereby rendering the enzyme permanently incapable of producing prostaglandins. This is what leads to aspirin's anti-inflammatory effects. Let's get a closer look at this activity now. • Script by Chris Hofmann • Watch the whole Pharmacology playlist: http://bit.ly/ProfDavePharma • General Chemistry Tutorials: http://bit.ly/ProfDaveGenChem • Organic Chemistry Tutorials: http://bit.ly/ProfDaveOrgChem • Biochemistry Tutorials: http://bit.ly/ProfDaveBiochem • Biology/Genetics Tutorials: http://bit.ly/ProfDaveBio • Anatomy Physiology Tutorials: http://bit.ly/ProfDaveAnatPhys • Biopsychology Tutorials: http://bit.ly/ProfDaveBiopsych • Microbiology/Infectious Diseases Tutorials: http://bit.ly/ProfDaveMicrobio • History of Drugs Videos: http://bit.ly/ProfDaveHistoryDrugs • Immunology Tutorials: http://bit.ly/ProfDaveImmuno • EMAIL► [email protected] • PATREON► / professordaveexplains • Check out Is This Wi-Fi Organic? , my book on disarming pseudoscience! • Amazon: https://amzn.to/2HtNpVH • Bookshop: https://bit.ly/39cKADM • Barnes and Noble: https://bit.ly/3pUjmrn • Book Depository: http://bit.ly/3aOVDlT

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