Nerve Physiology 🧠 Introduction to the Action Potential Physiology Playlist

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This video is about the general physiology of a nerve • (Potentials, Polarizations, Permeability, and Excitability) • Content: • 0:00 Introduction • 1:25 Basic Physiological Rules of a Cell • 3:25 Rules of Transport Across the Membrane • 3:36 Passive Transport • 6:24 Active Transport • 8:40 Membrane Potentials • 13:54 Action Potentials • 17:55 Impulse Conduction • 19:40 Saltatory Conduction • 20:25 All-or-None Law • ------------------------------- • 🫀Join: / @taimtalksmed • 📷 Follow my IG: / taimtalksmed • 💝 Donation link: https://www.buymeacoffee.com/taimtalk... • ------------------------------- • Basic physiological rules of the cell: • More negative inside the cell than on the outside. • Difference in extracellular and intracellular fluid • Nernst Equation calculates the charged ions across a membrane • Transport through the cell membrane: • Passive Transport: • Simple diffusion (has to be small, lipophilic and no charge) • Facilitated diffusion (Ion channel and Gated channels) • Filtration • Electrokinetic transport • Osmosis • Active Transport: • Primary Active Transport: Na/K Pump, Ca Pump • Secondary Active Transport: Na/Glucose, Na/Amino Acids, Na/H • Nerve: • Functionally divided into three parts: • Receptive Part: Dendrites • Integrating part: Cell body and Axon Hillock • Transmitting part: Axon • Resting Potential: • Typically -70 mV • Chemical gradient outside, Electrical Gradient inside = Electrochemical gradient outside • Sodium and Potassium goes in and out of cell throguh Ion Channels • Sodium potassium pump pumps 3 sodium out, 2 potassium in • Action potential: • Voltage-Gated Channels • Excitability • Two gates on VG-Channel - Activation gate and inactivation gate • Changes of excitability during an action potential • Permeability of cell membrane during different stages of action potential: • 1. resting state: Sodium and Potassium are unable to pass through the gated channels. Inside the cell: Negative • 2. Depolarization: Sodium starts flowing in, inside the cell: positive • 3. After depolarization comes repolarization, where the sodium channel close, and the potassium channel opens. Outflux of potassium brings cells back to more negative than the initial state (Hypoerloarization). This is the refractory period • Conduction of action potential through a nerve axon. • Continous Conduction (Unmyelinated) • Saltatory Conduction (Myelinated) • All-Or-None Law • Either we get a action potential, or not. • Chemical Synapse with Ligand gated channels, or chemically gated channels • Excitatory or Inhibitory • #nervephysiology #physiology #nerve #neuron #actionpotential

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