UREA CYCLE Part 1 BIOCHEMISTRY LECTURES PEDIATRICS LECTURES METABOLIC DISORDERS INICET NEETPG











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#UREACYCLE, Part 1, #UreaCycleDisorders #BIOCHEMISTRYLECTURES, #PEDIATRICSLECTURES, #METABOLICDISORDERS, #INICET, #NEETPG • The urea cycle (also known as the ornithine cycle) is a cycle of biochemical reactions that produces urea (NH2)2CO from ammonia (NH3). This cycle occurs in ureotelic organisms. The urea cycle converts highly toxic ammonia to urea for excretion. • Primary urea cycle disorders (UCDs) include carbamoyl phosphate synthase (CPS) deficiency, ornithine transcarbamylase (OTC) deficiency, argininosuccinate synthetase deficiency (citrullinemia), argininosuccinate lyase deficiency (argininosuccinic aciduria), and arginase deficiency (argininemia).

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