Role of Monocytes and Alpha1 Antitrypsin in ANCAAssociated Vasculitis

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0:00 Welcome and introductions. • 1:55 Current state of treatment for AAV. • 3:51 What are Monocytes? • 7:24 What is Alpha-1 Antitrypsin (A1AT)? • Role of Monocytes • Recorded July 2023 • Pulmonologist Lynn Fussner goes into detail on the work she is doing in ANCA-associated vasculitis (AAV), looking at advances in treatment, the role of monocytes and their relationship with alpha-1 antitrypsin, progress that has been made and next steps. Recorded July 2023 Presenter: Lynn Fussner, MD • ------------------------------------------------------------------------------------------------ • 18:58 Welcome and introductions • 19:09 Objective and background • 23:47 Conclusions • 26:27 Q A: Do you think the time it will take to do research will be shortened or enhanced by artificial technology? • 28:42 Q A: Should all patients with ANCA vasculitis see a cardiologist? • 30:14 Q A: Do you think research into other autoimmune diseases will help us find breakthroughs in vasculitis? • 32:36 Q A: Is it common for patients with MPA to first present with atrial fibrillation (AFib) • Alpha-1 Antitrypsin in ANCA-Associated Vasculitis • Recorded July 2023 • Dr. Arévalo discusses the aim of her study, which is to assess the cardiovascular risk in patients with vasculitis and diabetes mellitus and understand whether the risk of cardiovascular disease in patients with vasculitis is as high as in those with diabetes mellitus. • Expand your knowledge of vasculitis. Visit the Vasculitis Foundation website at: https://www.vasculitisfoundation.org/

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