The Basal Ganglia The direct and indirect pathways











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Every day you make hundreds of well-controlled movements, but have you ever wondered about what helps regulating them?! • And why some people with Parkinson disease or Huntington disease can’t fully control their movements? The answer is: Basal Ganglia, and this is our topic in this video. • We will discuss the anatomical component of the Basal Ganglia and their functions, the direct and the indirect pathways and their importance in regulating our movements. Moreover, we will talk about major abnormalities that can affect the basal ganglia including: Parkinson's disease, Huntington's Chorea, and Hemiballismus. • Contents: • 0:15 - Basal Ganglia definition and role • 0:53 - Nuclei of the basal ganglia • 1:52 - Basal ganglia neurotransmitters • 2:19 - Basic game plan of the basal ganglia • 3:02 - Direct pathway • 3:25 - Indirect pathway • 4:14 - Summary of direct and direct pathways • 4:25 - Regulation of direct and indirect pathways (Substantia Nigra) • 5:14 - Abnormalities • 5:31 - Parkinson's disease • 6:27 - Huntingotn's disease • 7:14 - Hemiballismus • 7:37 - Summary of extrapyramidal syndromes

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