Best Practices Lysing Matrices for Preclinical Samples MP Biomedicals











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Discover effective tissue homogenization tips to streamline your preclinical projects. • Preclinical research frequently involves homogenizing biological tissues to extract and isolate DNA, RNA, proteins, and metabolites for molecular analysis and various downstream applications. There are many considerations when selecting the appropriate lysing matrix for mechanically homogenizing your sample. • The most critical factor to consider is the resilience of your sample. Many biological samples are soft and easy to lyse, such as mammalian cells and brain tissue, but others are very resistant to lysing and homogenization, such as hair and skin. • Tougher samples often require more aggressive lysing matrices and sometimes unique conditions. • Read our pro tips: https://bit.ly/3uCw8Mi • or contact us at [email protected]

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