Gq Pathway Of GProteinCoupled Receptors Explained Clip

>> YOUR LINK HERE: ___ http://youtube.com/watch?v=KBJXkv4Cf2g

Welcome to Science With Tal! • In this video, we will cover the Gq pathway of the G-protein-coupled receptors (GPCRs). The Gq pathway is very important to understand, as it mediates many intracellular cascades in neurons and other types of cells. Through this discussion, we will discuss protein kinase C (PKC) and calcium-calmodulin dependent kinase (CaMK), which are 2 very important kinases in the body. • This conversation on neurons in the CNS derives from important concepts that are described in two previous full discussions: • 1- To watch the first part (Signal propagation in the Neuron), make sure to go to: • Signal Propagation In The Neuron (Neu... • 2- To watch the second (The Neuromuscular Junction as the model of the chemical synapse) make sure to go to: • Neuromuscular Junction As The Model F... • To improve the quality of my content, I highly value the feedback from the viewer so do not hesitate to give any feedback in the comment section. • TIMESTAMPS • 0:00 Introduction • 0:15 Gq pathway (PLC, PIP2, PKC, CaMK) • 4:16 Word on CaMK2 • 5:04 Summary of Gq pathway • 6:08 Conclusion • RESOURCES • Here is a list of the resources that I’ve used to produce this video. (Author(s): title resource) • Dale Purves: Neuroscience (6th edition) • Eric Kandel: Principles of neural science (6th edition) • Lodish: Molecular Cell Biology (9th edition) • Niswender, Colleen M, and P Jeffrey Conn: Metabotropic glutamate Receptors: physiology, pharmacology, and disease • Bünemann, M et al: Activation and deactivation kinetics of alpha 2A- and alpha 2C-adrenergic receptor-activated G protein-activated inwardly rectifying K+ channel currents • Howlett, Allyn C et al: CB(1) cannabinoid receptors and their associated proteins • Morris, R G: D.O. Hebb: The Organization of Behavior, Wiley: New York; 1949 • Stent, G S: A physiological mechanism fo Hebb’s postulate of learning • To have more information on these resources, you can refer to the conclusion section where a more formal citation is provided. • CREDITS • Writing: Tal Klimenko • Voice: Tal Klimenko • Animations: Tal Klimenko • Drawings: Tal Klimenko • Editing: Tal Klimenko • Introductory jingle: Thierry Du Sablond • Conclusion music: lukrembo - sunflower ( • lukrembo - sunflower (royalty free vl... )

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