Youtor
Upjohn Dihydroxylation amp Cleavage of 12Diols with NaIO4 IOC 28
>> YOUR LINK HERE: ___ http://youtube.com/watch?v=KFB1dQ_dW8M
In this episode, I discuss the dihydroxylation of alkenes (Upjohn Dihydroxylation) oxidative cleavage of 1,2-diols using NaIO4 (the Malaprade Reaction). When these two reactions are done together, it is known as Lemieux–Johnson oxidation. • ---------------------------------------------------------------------------------------------------------------------------------- • Links to articles discussed in this episode: • Upjohn alkyne oxidation - https://doi.org/10.1021/cr60324a003 • OsO4 review - https://doi.org/10.1002/047084289X.ro... • first Upjohn - https://doi.org/10.1021/ja908626k • second Upjohn - https://doi.org/10.1055/s-0034-1378902 • NaIO4 review - https://doi.org/10.1002/047084289X.rs... • first NaIO4 - https://patents.google.com/patent/WO2... • second NaIO4 - https://doi.org/10.1080/15257770.2013... • first Lemieux–Johnson oxidation - https://doi.org/10.3390/molecules2617... • second Lemieux–Johnson oxidation - https://doi.org/10.1248/cpb.c16-00147 • ---------------------------------------------------------------------------------------------------------------------------------- • I hope you enjoyed the video! I'm planning on making a full series of videos if these videos are helpful for people! • Recommended Texts: • J. Clayden, N. Greeves, S. Warren, Organic Chemistry Second Edition, Oxford University Press, 2012. (especially good for mechanism and physical chemistry explanations) • T. W. G. Solomons, C. B. Fryle, S. A. Snyder, Organic Chemistry Twelfth Edition, Wiley-VCH Verlag GmbH Co. KGaA, 2016. • LibreTexts: • https://chem.libretexts.org/Bookshelv...
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