How do mRNA COVID19 vaccines work

>> YOUR LINK HERE: ___ http://youtube.com/watch?v=KMc3vL_MIeo

Leading COVID-19 vaccine candidates rely on new technologies that have fast-tracked development and testing. Vaccines from Pfizer and Moderna have completed early phase 3 clinical trials and are reportedly under review at the US FDA for emergency use authorization (EUA) although safety surveillance continues. This video explains the principles underlying the leading DNA, messenger RNA (mRNA), and viral vector vaccine candidates, and how they might induce immunity to SARS-CoV-2 infection. • 0:00 Introduction • 1:21 Traditional vaccines • 2:00 COVID-19 vaccine types in development • 2:18 Making vaccines from a genetic sequence • 2:45 Target antigen: the S protein • 3:32 Genetic vaccines (DNA and mRNA) • 4:18 Moderna/NIH and Pfizer/BioNTech vaccines • 4:52 Viral vector vaccines • 5:42 Adenovirus vectors (University of Oxford/AstraZeneca and Johnson Johnson/Janssen Pharmaceuticals) • 6:32 rVSV vector vaccine (Merck/IAVI) • 7:15 Previous experience with next generation vaccines • 7:50 Importance of Phase 3 Trials • For full livestreams featured in this video: • Anthony S. Fauci, MD, January 27, 2020: • The 2019 Coronavirus Outbreak – What ... • Paul A. Offit, MD, June 1, 2020: • Coronavirus Vaccine Development • Robert Redfield, MD, July 14, 2020: • Coronavirus Update With CDC Director,... • --------------------------------------------------------------------------------- • • Coronavirus Resource page from the JAMA Network: https://ja.ma/covidyt • • To watch JAMA Live Q A's Visit: https://ja.ma/covidqaytpl • • Don't forget to hit subscribe or click https://ja.ma/subscribe • For more from JAMA • • https://www.jama.com • • / jamajournal • • / jama_current • • / jamanetwork • Follow the JAMA Network • • https://www.jamanetwork.com • • http://www.jamanetworkaudio.com • • / jamanetwork • • / jamanetwork • • / jamanetwork • • / jamanetwork

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