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Topoisomerase Inhibitor Irinotecan Topotecan Etoposide Teniposide
>> YOUR LINK HERE: ___ http://youtube.com/watch?v=PH35VZbVCzw
#pharmacology #anticancer #chemotherapy #cancertreatment #irinotecan #topotecan #etoposide • Topoisomerase I inhibitors are a new class of anticancer agents with a mechanism of action aimed at interrupting DNA replication in cancer cells, the result of which is cell death. Most if not all Topoisomerase I inhibitors are derivatives of the plant extract camptothecin. • Topoisomerase inhibitors in current use in the United States include irinotecan and topotecan, inhibitors of topoisomerase I, and etoposide and teniposide, inhibitors of topoisomerase II. All four agents are semisynthetic analogues of natural toxins that were initially identified in plants.
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