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PDF link • https://drive.google.com/file/d/1PwlM... • #Hyperlipidamia • #DefinitionOfhyperlipidamia : • Hyperlipidamia is a condition in which levels of lipids ( especially cholesterol and triglyceride ) increased in blood . • • #Etiology_of_Hyperlipidamia • 1) too much alcohol consumption . • 2) taking foods , high in saturated fat • 3) No physical activity , spending most time sitting . • 4) genetic problem • Some drugs that can increase cholesterol levels • 1) ß blockers • 2) Diuretics • 3) Hormonal birth control pills • 4) Steroids • Some diseases can increase cholesterol levels : • 1) Hypothyrodism • 2) chronic kidney disease • 3) diabetes • 4) HIV • #Pathogenesis _of_Hyperlipidamia • Liver produces cholesterol to help in digestion and taking too much meat and dairy products in diet increase fat in our body and causes hyperlipidamia . • #Normal_Cholesterol_levels • Types of cholesterol Normal range • Total cholesterol Less than 200mg/dl • Triglyceride Less than 150mg/dl • Bad cholesterol ( LDL) Less than 100 mg / dl • Good cholesterol ( HDL) At least 60 mg / dl • #Clinical_Manifestation_of_hyperlipidamia • Hyperlipidamia does not show any symptoms , although at high level .but may lead to other condition like : • 1) high blood pressure • 2) heart attack • 3) stroke ( reduce blood supply to brain ) • #Non_pharmacological_management_of_Hyperlipidamia • 1) Exercising • 2) Leaving alcohol drinking • 3) getting good sleep at least 6-7 hours at every night • 4) Maintaining body weight and obesity • 5) avoiding too much meat and dairy product • #Pharmacological_management_of_Hyperlipidamia • 1) #Statins : these drugs prevent liver from producing cholesterol e.g. atorvastatin , Fluvastatin • 2) #Cholesterol_Absorption_Inhibitors : these drugs prevent cholesterol absorption from intestine . These drugs work in combination with statins .e.g. Ezetimibe , simvastatin . • 3) Nicotinic Acids : It reduce LDL and triglyceride , and increases HDL . e.g. Niacin . • 4) #fibrates : Clofibrates , Fenofibrates . • 5) #Resins : Colestipol , Colesevelam . • #Hyperlipidamiabysrpharmacy • #Pharmacotherpeuticshyperlipidamia • ‪@srpharmacy‬ • #srpharmacy

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