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For more information visit https://www.miltenyibiotec.com/applic... Human mesenchymal stromal or stem cell (MSC)-based immunomodulation treatment has been proposed as a suitable therapeutic approach for many diseases, including COVID-19. • We have developed a GMP-compliant workflow for MSC manufacturing to facilitate efficient clinical translation. The new CliniMACS Prodigy® Adherent Cell Culture System increases the level of process standardization and product safety. The closed system facilitates manufacturing steps, such as feeding, replating, expanding, and harvesting procedures. When working with human bone marrow samples, the included density gradient centrifugation module can easily isolate bone marrow mononuclear cells. • https://www.miltenyibiotec.com/produc... • https://www.miltenyibiotec.com/produc... • Our xeno-free MSC-Brew GMP Medium, manufactured following the recommendations of USP '1043' on ancillary materials, enables efficient expansion of MSCs from different tissue sources including human bone marrow, adipose tissue, and umbilical cord. Together with the Adherent Cell Culture System, over 200 million MSCs can be generated from a single donor sample in just 14 days. • Cultured MSCs need to go through strict quality control before being used in any clinical application. Our new MSC Phenotyping Kit, human includes three positive and five negative MSC markers based on the ISCT standard and facilitates standardized and reliable phenotyping of cultured human MSCs from different tissue sources. The highly pure and recombinantly engineered REAfinity™ Recombinant Antibodies ensure high lot-to-lot consistency and reproducible results in flow cytometry. • Miltenyi Biotec is a global provider of products and services that advance biomedical research and cellular therapy. Our innovative tools support research at every level, from basic research to translational research to clinical application. This integrated portfolio enables scientists and clinicians to obtain, analyze, and utilize the cell. Our technologies cover techniques of sample preparation, cell isolation, cell sorting, flow cytometry, cell culture, molecular analysis, and preclinical imaging. Our 30 years of expertise spans research areas including immunology, stem cell biology, neuroscience, and cancer, and clinical research areas like hematology, graft engineering, and apheresis. In our commitment to the scientific community, we also offer comprehensive scientific support, consultation, and expert training. Today, Miltenyi Biotec has 2,500 employees in 28 countries – all dedicated to helping researchers and clinicians around the world make a greater impact on science and health.
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