Youtor
Rheumatoid Arthritis Pharmacology DMARDs TNF Îą and IL1 Inhibitors
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ðððžðķðŧ ðĒððŋ ð§ðēðđðēðīðŋðŪðš ððĩðŪðŧðŧðēðđ ððēðŋðē:- https://t.me/bhanuprakashdr • ð ð ðĻðĨðĨðĻð° ðĻð§ ðð§ðŽððð ðŦððĶ:- / drgbhanuprakash • ððĶððŊðð°ðŋðķðŊðē ð§ðž ð ð ð ðŪðķðđðķðŧðī ððķðð:- https://linktr.ee/DrGBhanuprakash • Rheumatoid Arthritis Pharmacology - DMARDs, TNF- α and IL-1 Inhibitors - • -------------------------------------------------------------------------------------------------------------------------Rheumatoid arthritis (RA) is an autoimmune disorder that leads to chronic inflammation of the joints, causing pain, stiffness, and long-term joint damage. ðĶīðĨ The pharmacologic management of RA focuses on modifying the disease course and relieving symptoms, with the primary agents being Disease-Modifying Anti-Rheumatic Drugs (DMARDs). DMARDs, like methotrexate, sulfasalazine, and hydroxychloroquine, work to slow or even stop the immune system from attacking joint tissue, providing relief and halting joint destruction. ðĐšð • In addition to traditional DMARDs, biologic DMARDs have become a cornerstone in RA treatment, specifically targeting inflammatory mediators like TNF-α (Tumor Necrosis Factor-alpha) and IL-1 (Interleukin-1), which play central roles in the inflammatory cascade. TNF-α inhibitors, such as infliximab, etanercept, and adalimumab, work by neutralizing TNF-α, reducing inflammation and minimizing joint damage. These inhibitors are especially effective in patients who don’t respond adequately to conventional DMARDs. ð𧎠• IL-1 inhibitors, like anakinra, focus on blocking IL-1, another pro-inflammatory cytokine that promotes joint degradation and inflammation in RA. By inhibiting these cytokines, IL-1 inhibitors help protect joint integrity, though they are used less frequently than TNF-α inhibitors due to specific indications and varying patient responses. ðŽ • While these medications offer tremendous benefits, they also require monitoring for potential side effects, especially infections, due to immune suppression. ððŠðð • #RheumatoidArthritis #DMARDs #TNFInhibitors #IL1Inhibitors #AutoimmuneDisease #Pharmacology #MedicalEducation #JointHealth #RAWarriors #Healthcare #medicalanimations #fmge #fmgevideos #rapidrevisionfmge #fmge2024 #mbbslectures #nationalexitexam #nationalexittest #neetpg #usmlepreparation #usmlestep1 #fmge #usmle #drgbhanuprakash #medicalstudents #medicalstudent #medicalcollege #neetpg2025 #usmleprep #usmlevideos #usmlestep1videos #medicalstudents #neetpgvideos #usmlestep2videos
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