Prions Prions Disease Transmissible Spongiform Encephalopathies Diagnosis and treatment











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Prions are misfolded proteins that can cause misfolding of normal variants of the same protein and trigger cellular death. Prions cause prion diseases, also known as transmissible spongiform encephalopathies (TSEs), which are transmissible, fatal neurodegenerative diseases in humans and animals. The proteins may misfold sporadically, due to genetic mutations, or by exposure to an already misfolded protein. The consequent abnormal three-dimensional structure confers on them the ability to cause misfolding of other protein. • #Prions

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