Bartonella Treatment Antibiotics Basics Clarithromycin Rifampin Rifabutin My Experience FAQs











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I review the basics of the antibiotic protocol that I intend on taking, once my mast cell activation is better controlled. I intend on taking this protocol based on the expertise of my two Bartonella literate medical doctors and my own anecdotal experience. I then address some common questions about this protocol. • ✩ WAYS TO SUPPORT MY HARD WORK • I believe that everyone should have access to affordable, high-quality healthcare and I also believe that people should be compensated for their hard work. If you appreciate my hard work, research, and advocacy, you can also support me in the following ways: • → PayPal: username @bartonellababe or search Jake Picker • → Venmo: username Jake-Picker • ✩ No one needs to support me in this way and please do not gift me if you are not in a position to do so! • → SHOP MY MERCH HERE: https://bartonella-babe.creator-sprin... • → SHOP MY JEWELRY HERE: https://www.etsy.com/shop/bartonellababe • ✩ Thank you for supporting my hard work and my channel! See more ways to support my channel below. • ✩ 25% of all MERCH proceeds go to the Bartonella Project at the North Carolina State University College of Veterinary Medicine. Link to donate directly to the Bartonella Project: • https://securelb.imodules.com/s/1209/... • Let's connect! • ✩Instagram: @bartonella_babe • ✩Facebook: www.facebook.com/bartonellababe • ✩Inquiries: [email protected] • JOIN our bartonellosis support group on Facebook called BREAKING DOWN BARTONELLA: •   / 1104493829902071   • Time stamps: • 0:00 Intro • 1:32 Basics of the antibiotic protocol • 5:02 Why did I choose this protocol? • 7:43 My experience with this protocol • 11:23 Why use clarithromycin over azithromycin? • 13:35 CYP3A4 pathway introduction • 14:25 Interactions between clarithromycin and the rifamycins • 14:37 CYP3A4, cortisol, hormones, and prescription drugs • 15:27 Interactions between clarithromycin and rifampin • 16:26 Interactions between clarithromycin and rifabutin • 16:54 Neutropenia and raised liver enzymes (ALT, AST) • 18:16 Uveitis • 19:45 Why use hydrocortisone? Aren't steroids bad to use with infections? • 21:17 How and when should I take my antibiotics? • 21:47 Why not doxycycline or other antibiotics? • 22:49 This protocol seems too long/aggressive • 24:27 Future videos on treatment • Videos referenced: • Galaxy's webinar with Dr. Mozayeni (and Dr. Breitschwerdt):    • Understanding Bartonella Webinar_Edited   • Jack and Amy's bartonellosis success story!:    • Jack And Amy's Bartonellosis Success ...   • Studies referenced: • 1. Biswas, S., Maggi, R. G., Papich, M. G., Breitschwerdt, E. B. (2010). Molecular mechanisms of Bartonella henselae resistance to azithromycin, pradofloxacin and enrofloxacin. Journal of antimicrobial chemotherapy, 65(3), 581-582. • 2. Kazama, I., Saito, K., Baba, A., Mori, T., Abe, N., Endo, Y., ... Yamauchi, M. (2016). Clarithromycin dose-dependently stabilizes rat peritoneal mast cells. Chemotherapy, 61(6), 295-303. • 3. McDonnell, A. M., Dang, C. H. (2013). Basic review of the cytochrome p450 system. Journal of the advanced practitioner in oncology, 4(4), 263. • 4. Wallace Jr, R. J., Brown, B. A., Griffith, D. E., Girard, W., Tanaka, K. (1995). Reduced serum levels of clarithromycin in patients treated with multi-drug regimens including rifampin or rifabutin for Mycobacterium avium-M. intracellulare infection. Journal of Infectious Diseases, 171(3), 747-750. • 5. Hafner, R., Bethel, J., Power, M., Landry, B., Banach, M., Mole, L., ... Cohn, D. (1998). Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers. Antimicrobial agents and chemotherapy, 42(3), 631-639. • 6. Griffith, D. E., Brown, B. A., Girard, W. M., Wallace Jr, R. J. (1995). Adverse events associated with high-dose rifabutin in macrolide-containing regimens for the treatment of Mycobacterium avium complex lung disease. Clinical infectious diseases, 21(3), 594-598. • 7. Aronson, J. K. (Ed.). (2015). Meyler's side effects of drugs: the international encyclopedia of adverse drug reactions and interactions. Elsevier. • 8. Crabol, Y., Catherinot, E., Veziris, N., Jullien, V., Lortholary, O. (2016). Rifabutin: where do we stand in 2016?. Journal of Antimicrobial Chemotherapy, 71(7), 1759-1771. • 9. Zimran, E., Shilo, S., Florescu, T., Dotan, S., Balag, S., Mevorach, D., ... Amer, R. (2012). Paradoxical response in ocular bartonellosis. Journal of ophthalmic inflammation and infection, 2(1), 53-56. • Best diagnostic testing: • www.galaxydx.com • Dr. B. Robert Mozayeni's research use only confocal laser scanning microscope with fluorescent tags for Bartonella henselae: • https://www.tlabdx.com/ • #Bartonellosis #Bartonella #Bartonellatreatment #BartonellaBabe

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