Metals in medicine Diagnostic and therapeutic agents
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Several metals, including iron, cobalt, copper and zinc, are naturally present in living organisms and play essential roles in a wide range of biological processes. In addition, some metal complexes have shown to be very successful therapeutic and diagnostic agents. Examples of these are platinum-based anticancer drugs, used in chemotherapy since the 1970s, and gadolinium-based MRI contrast agents for medical imaging. • For several years Ramon Vilar and his team have been studying the chemistry of metal complexes in living organisms with the aim of developing new metal-based drugs as well as gaining a better molecular understanding of biological processes. They have a particular interest in studying how novel metal complexes interact with selected enzymes and DNA. • For more information please visit http://www3.imperial.ac.uk/newsandeve...
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