Mayo Clinic Minute Lift your mood with light therapy

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Click Here to Subscribe: http://Bit.ly/ThomasVid • Check out Joovv's Red Light Therapy Devices: http://www.joovv.com/Thomas • My Website: http://ThomasDeLauer.com • Red Light Therapy | 5 Reasons to Try Photobiomodulation | Bio-Hacking (Scientific Results) • Benefits: • Anti-Inflammatory- • Red light therapy limits the inflammatory response and reduces oxidative damage by reducing inflammatory cytokines (TNF-a, IL-1A, and IL-6) • Skin/Joint/Hair Health: • LLLT aids skin rejuvenation through increasing collagen production. Increase in collagen production occurs by LLLT’s increasing effects on PDGF (platelet-derived growth factor) and fibroblast production which happens through decreasing apoptosis, increasing vascular perfusion, bFGF and TGF-β • Sleep: • Regulation of melatonin and temperature is controlled by the suprachiasmatic nucleus (SCN) in the hypothalamus of the brain, which fluctuates cyclically but needs an external stimulus to maintain a consistent 24-hour cycle. The mechanism of light therapy for sleep is believed to be via stimulation of the SCN, effectively correcting the timing and/or strengthening the amplitude body’s circadian cycles. • Study - Journal of Athletic Training: • Twenty athletes (considered elite female basketball players) were divided into red-light treatment (n = 10) and placebo (n = 10) groups. The red-light treatment participants received 30 minutes of irradiation from a red-light therapy every night for 14 days - the placebo group did not receive light illumination. The Pittsburgh Sleep Quality Index (PSQI) questionnaire was completed, serum melatonin was assessed, and 12-minute run was performed at pre intervention (baseline) and post intervention (14 days.) The 14-day whole-body irradiation with red-light treatment improved the sleep, serum melatonin level, and endurance performance of the subjects. Specifically, they found that at pre-intervention, there was no difference between the red-light treatment (22.2 ± 7.2 pg/mL) and placebo (21.7 ± 6.8 pg/mL) groups (Picograms Per Millilitre.) At post intervention, participants in the red-light treatment group (38.8 ± 6.7 pg/mL) demonstrated greater improvement in serum melatonin level than the placebo group (23.8 ± 7.3 pg/mL • https://www.ncbi.nlm.nih.gov/pubmed/2... • Performance Recovery: • Study - Lasers in Medicinal Science- • A single phototherapy intervention was performed immediately after pre-exercise (baseline) maximum voluntary contraction (MVC) with red light or placebo in six sites of quadriceps. • MVC is a standardized method for measurement of muscle strength in patients • MVC, delayed onset muscle soreness (DOMS), and creatine kinase (CK) activity were analyzed. Assessments were performed before, 1 min, 1, 24, 48, 72, and 96 h after eccentric exercise protocol employed to induce fatigue. Phototherapy increased MVC was compared to placebo from immediately after to 96 h after exercise. DOMS was significantly decreased compared to placebo from immediately after to 96 h after exercise. CK activity was significantly decreased compared to placebo with phototherapy as well. • Possible Mechanisms: • Some physiological effects attributed to red light therapy are related to soft tissue metabolism: • Across different disorders, increased microcirculation, enhanced ATP synthesis, and stimulation of mitochondrial respiratory chain and mitochondrial function have been observed after red light therapy. • Reduction of ROS release and creatine phosphokinase activity, and increased production of antioxidants and heat shock proteins are believed to play a role here. • For Neurodegeneration: • Red light therapy has been reported to induce reductions in β-amyloid plaques, together with increased ATP levels and improved overall mitochondrial function. Red light therapy treatment increases ATP levels and overall cell number, while reducing β-amyloid plaques. First, RLT acts at a cellular level, activating intracellular cascades that ultimately contribute to the survival of the target, and possibly neighboring, cells and/or stimulating neurogenesis. Second, RLT appears capable of triggering systemic protective mechanisms; this presumably involves as yet unidentified circulating cellular or humoral factors that can transduce protective effects to the brain. • Resources: • 1) https://www.ncbi.nlm.nih.gov/pubmed/2... • 2)https://www.academia.edu/33385816/Pho... • 3)https://www.medicalnewstoday.com/arti... • 4)https://www.ncbi.nlm.nih.gov/pmc/arti... • 5)https://www.ncbi.nlm.nih.gov/pmc/arti... • 6)https://www.ncbi.nlm.nih.gov/pmc/arti... • 7)https://www.ncbi.nlm.nih.gov/pmc/arti...

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