Introduction to Metagenomics

>> YOUR LINK HERE: ___ http://youtube.com/watch?v=WnluVyJ58xw

This is the first module of the Analysis of Metagenomic Data 2018 workshop hosted by the Canadian Bioinformatics Workshops at the Ontario Institute for Cancer Research. This session is by William Hsiao from the University of British Columbia. • Table of Contents: • 00:59 - Course overview • 04:53 - General Learning Objectives • 06:06 - Learning objectives of Module 1 • 07:14 - Defining Metagenomics • 10:08 - The big picture • 11:47 - Why metagenomics? • 14:26 - Turkey Microbiome • 15:18 - Turkey Microbiome –why do we care? • 16:25 - Turkey Microbiome – can impact human • 17:01 - From Turkey to Turkish Drink • 17:02 - Turkey Microbiome – can impact human • 17:06 - From Turkey to Turkish Drink • 18:44 - Most of you is not you…. • 19:53 - • 20:16 - Sequencing technologies • 21:00 - Sequencing Run Capacity • 21:01 - Sequencing technologies • 22:12 - Sequencing Run Capacity • 22:21 - What can Microbiome Studies Answer? • 23:17 - What’s in the microbiome? • 23:23 - What can Microbiome Studies Answer? • 23:26 - What’s in the microbiome? • 24:00 - What functions are present in the microbiome? • 26:26 - What does the microbiome correlate with? • 27:59 - How will the microbiome respond? • 30:41 - A Brief History of Metagenomics and Things Like It • 30:54 - • 31:43 - Staden (1979) • 31:44 - • 32:01 - Staden (1979) • 33:17 - • 33:19 - • 33:28 - • 33:29 - • 33:53 - • 34:20 - • 35:30 - • 36:38 - • 36:48 - Major concerns in metagenomic analysis • 36:49 - • 37:39 - Major concerns in metagenomic analysis • 37:47 - Data Quality • 41:05 - Minimal Metadata about a Microbiome Experiment • 43:44 - Comparability / Reproducibility • 45:34 - Linkage and resolution • 47:03 - Taxonomy and OTUs • 48:14 - Functional annotation problems • 49:56 - Resources • 50:03 - 16S • 50:33 - Genomes • 51:30 - “Metagenomes” • 52:30 - Function • 53:49 -

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