EASD 2023

YOUR LINK HERE:

http://youtube.com/watch?v=Wv_8DiZPOkY

Despite past setbacks and the failure of larger artificial pancreas projects, Professor Roman Hovorka's dedication to creating closed-loop delivery systems for an artificial pancreas has never wavered. Born in the Czech Republic, Havok began his career in a university hospital, where he saw the potential to help people with diabetes by modeling metabolic processes. • In the video, Havok shares his journey from studying mathematical informatics to spearheading clinical trials and establishing the JDRF Artificial Pancreas Consortium. Researchers discuss the development of a closed-loop insulin delivery system for type 1 diabetes, focusing on error prevention and safety measures. Clinical trials at Adam Brooks Hospital in Cambridge tested the system on children, whose unpredictable eating patterns and faster metabolism presented unique challenges. The team navigated the complex process of developing medical devices and establishing a company, resulting in significant quality of life improvements for participants, who described it as a diabetes holiday. • Havok shares a personal connection to the project, having lost a friend to a nighttime hypoglycemic event. Today, several closed-loop systems are available for people with type 1 diabetes, marking a significant advancement in diabetes management until a cure is found. • 00:00 - Introduction to Insulin and Artificial Pancreas • 00:24 - Early Development Challenges • 00:42 - Introduction to Professor Roman Hovorka • 01:06 - Continuous Glucose Monitor and Artificial Pancreas • 01:41 - Roman Havok's Background and Early Career • 02:32 - Initial Skepticism and Early Efforts in Artificial Pancreas Development • 03:42 - Establishment of Research Group and Collaboration with JDRF • 04:34 - Safety Measures and Clinical Trials in Children • 05:40 - Challenges of Building a System for Children • 06:30 - Impact of Clinical Trials and User Feedback • 07:30 - Conclusion and Current Availability of Closed Loop Systems

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