Applied Computational Genomics 06 SAM BAM CRAM format











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From Aaron Quinlan's course on Applied Computational Genomics at the University of Utah (https://github.com/quinlan-lab/applie.... This lecture covers how DNA sequence mappings and alignments are represented in SAM/BAM/CRAM format. The lecture introduces the core attributes of the SAM format such as the CIGAR string and the bit-packing in the FLAG field. It also introduces the use of samtools for manipulating SAM/BAM/CRAM files.

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