Breaking Down Amino Acids Part 10 Metabolism Foundations Nourishable Macronutrients Lecture 26

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Amino acids are broken down through deamination and shuffling the carbon skeletons into acetylCoAs or Krebs intermediates. Subscribe to Nourishable at / nourishable • This video is part 10 of the Metabolism Foundations within a lecture series on the nutrition science of macronutrients. • • Metabolism Foundations Lecture playlist: • Metabolism Foundations • Macronutrients Lecture playlist: • Macronutrients Lectures • Follow Nourishable on twitter, facebook and instagram to stay up to date on all things nutrition. • / nourishable • fb.me/nourishable.tv • / nourishable • Lecture Development, Hosting Post-Production by Lara Hyde, PhD • http://www.nourishable.tv • Video Production by Robbie Hyde • / chedderchowder • Opening Motion Graphics by Jay Purugganan https://www.c9studio.com/WP/ • The information in this video is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. All content, including text, graphics, images and information, contained on or available through this video is for general information purposes only. • References • Chapter 9 Wardlaw’s Perspectives in Nutrition, 2019 (Editors: Byrd-Bredbenner, Moe, Berning and Kelley, 11th edition) • Images • Photo by Artem Podrez from Pexels • Proteins are composed of long strings of amino acids. Proteolysis is the process of breaking down the protein into individual amino acids. The nitrogen containing amine group is then removed through the process of deamination. The toxic ammonia from the amine group will go through the urea cycle to be converted into the harmless urea compound which can be excreted in the urine. The 20 different amino acids have differently shaped carbon skeletons. Some of these carbon skeletons can be shuffled to form Krebs cycle intermediates or pyruvate. These are called glucogenic amino acids because their carbon skeletons can be used in gluconeogenesis to build glucose. Other carbon skeletons can be rearranged to form acetylCoA. These are ketogenic amino acids because they can be used in ketogenesis to make ketones.

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