Youtor
Pulmonary Arterial Hypertension PAH Pharmacology
>> YOUR LINK HERE: ___ http://youtube.com/watch?v=Z2dhYpxYGEw
📌𝗝𝗼𝗶𝗻 𝗢𝘂𝗿 𝗧𝗲𝗹𝗲𝗴𝗿𝗮𝗺 𝗖𝗵𝗮𝗻𝗻𝗲𝗹 𝗛𝗲𝗿𝗲:- https://t.me/bhanuprakashdr • 📌 𝐅𝐨𝐥𝐥𝐨𝐰 𝐨𝐧 𝐈𝐧𝐬𝐭𝐚𝐠𝐫𝐚𝐦:- / drgbhanuprakash • 📌𝗦𝘂𝗯𝘀𝗰𝗿𝗶𝗯𝗲 𝗧𝗼 𝗠𝘆 𝗠𝗮𝗶𝗹𝗶𝗻𝗴 𝗟𝗶𝘀𝘁:- https://linktr.ee/DrGBhanuprakash • Pulmonary Arterial Hypertension (PAH) Pharmacology Overview 🌬️💊 • Pulmonary Arterial Hypertension (PAH) is a chronic, progressive condition marked by high blood pressure in the pulmonary arteries, leading to increased strain on the right side of the heart. Pharmacological management of PAH focuses on dilating pulmonary arteries, reducing vascular remodeling, and improving exercise tolerance, ultimately aimed at slowing disease progression. Major drug classes include Endothelin Receptor Antagonists (ERAs) like bosentan and ambrisentan, which block endothelin-1's vasoconstrictive effects. Phosphodiesterase-5 (PDE-5) Inhibitors such as sildenafil and tadalafil work by increasing nitric oxide availability, relaxing pulmonary vascular smooth muscle. Prostacyclin Analogs (e.g., epoprostenol, treprostinil) and Prostacyclin Receptor Agonists (e.g., selexipag) mimic the vasodilatory effects of prostacyclin, reducing pulmonary vascular resistance. Another class, Soluble Guanylate Cyclase (sGC) Stimulators like riociguat, enhances nitric oxide signaling, leading to pulmonary vasodilation. Combination therapies are often adopted for refractory cases, where drugs with synergistic effects are paired to improve patient outcomes. Regular monitoring of liver function, blood pressure, and renal status is critical for safe management. Early pharmacologic intervention is essential to optimize quality of life and prevent PAH-related complications. 🌡️💪 • #PulmonaryArterialHypertension #PAHTreatment #Pharmacology #PAHMedications #PAHPathophysiology #EndothelinReceptorAntagonists #PDE5Inhibitors #ProstacyclinTherapy #SGCStimulators #NEETPG #FMGE #USMLE #MedicalEducation #Cardiology #InternalMedicine #PAH #medicalanimations #fmge #fmgevideos #rapidrevisionfmge #fmge2024 #mbbslectures #nationalexitexam #nationalexittest #neetpg #usmlepreparation #usmlestep1 #fmge #usmle #drgbhanuprakash #medicalstudents #medicalstudent #medicalcollege #neetpg2025 #usmleprep #usmlevideos #usmlestep1videos #medicalstudents #neetpgvideos #usmlestep2videos
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