Homology modeling using Modeller Tutorial for beginners Part 1

>> YOUR LINK HERE: ___ http://youtube.com/watch?v=Zb98mmfnsvg

#Structure #Modeling #Proteins #Tutorial #Easy #Guide #Proteomics • 1 Go to the website of MODELLER https://salilab.org/modeller/ • 2 Firstly, You need to get a license to download a software • 3 Go to the registration page and get a licensekey using this link https://salilab.org/modeller/registra... • 4 Prereq for running a Modeller is Python https://www.python.org/downloads/rele... • 5 Modeller is a python based software for modelling the proteins. • 6 Go to NCBI ,search for the desired protein and download its FASTA file. • 7 After downloading , go to the documentation of Modeller software and save the file according to the format. • 8 Remove the header line, add steric at the end of the sequence and save the file with .ALI extension. • 9 While using BLAST, you can also find out the best possible hits for your query sequence. • 10 Choose the first 4 on the basis of high percentage identity. • 11 Go to RCSB PDB and download the template PDB files by their accession number. • 12 Now save all the files in the Modeller directory. • • Blog: https://farhanhaqjahangiri.blogspot.com/ • Youtube: / farhanhaqj

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