Why is TB still the deadliest infectious disease Wellcome

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It’s preventable. It’s curable. And millions are still dying. • Over the last 100 years, tuberculosis research has saved countless lives. Yet, despite such a legacy, it has failed to curb the epidemic. In this explainer video, featuring Professor Willem Hanekom and Professor Henry Mwandumba, we dive deeper into the reasons behind the current TB health crisis. Progress has been slow and funding is on the decline — but a tuberculosis-free world isn’t completely out of the question, right? • 00:00 Introduction • 00:17 Deadly TB infection rates • 01:22 The problem with the BCG vaccine • 02:19 TB diagnosis and treatment • 03:11 The missing millions • 04:24 Multi-drug resistant TB • 04:49 The current situation • 05:39 Positive TB updates • 🔔 Subscribe to Wellcome on YouTube: https://wellc.me/3Blh0c1 • 📚 SOURCES AND READING: • This video was adapted from an article we wrote in 2023: https://wellcome.org/news/tuberculosi... • For a thorough breakdown of the latest TB data, read the WHO Global Tuberculosis Report 2023: https://www.who.int/teams/global-tube... • In the video, we highlighted some articles on the ‘missing millions’: • https://doi.org/10.1136/bmjgh-2020-00... • https://pubmed.ncbi.nlm.nih.gov/31178... • https://doi.org/10.1371/journal.pmed.... • Venkatesan, P. published an article on TB funding compared to Covid-19: https://doi.org/10.1016/S1473-3099(22... • Treatment Action Group has even more data on TB funding over the years: https://www.treatmentactiongroup.org/... • All information about the TB Vaccine Accelerator Council can be found here: https://www.who.int/initiatives/tuber... • In our conclusion, we highlighted some reports on potential new vaccines for TB: • https://doi.org/10.1056/NEJMoa1909953 • https://www.sciencedirect.com/science... • 💬 SOCIAL MEDIA: • Follow us on Twitter: / wellcometrust • Follow us on Instagram: / wellcometrust • Connect with us on LinkedIn: / wellcome-trust • Find us on Facebook: / wellcometrust • 🔗 MORE FROM WELLCOME: • Wellcome is a global charitable foundation. We want everyone to benefit from science’s potential to improve health and save lives. • Read our latest stories, opinions and reports: https://wellcome.org/news-and-reports • Learn more about our work: https://wellcome.org/what-we-do • Find our latest funding opportunities: https://wellcome.org/grant-funding

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