Coronavirus Update 116 Pfizer COVID 19 Vaccine Explained Biontech











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Professor Roger Seheult, MD discusses the Pfizer / Biontech COVID-19 mRNA vaccine: How it works and what we know about the safety and efficacy at this time. • No mRNA vaccine has ever been approved by the FDA, but Pfizer and BioNTech hope to receive emergency approval based on preliminary data from their ongoing vaccine trial. • This two-dose vaccine regimen has limitations including the need for -70 C refrigeration and many questions remain: • Will the vaccine prevent transmission and asymptomatic spread? • How long will immunity last? • Will “90% effective” hold up to peer-review and additional data when it is gathered? • (This video was recorded on November 12, 2020). • Dr. Seheult is the co-founder and lead instructor at https://www.medcram.com/?utm_source=Y... • • LINKS / REFERENCES: • Johns Hopkins Tracker | https://coronavirus.jhu.edu/map.html • Worldometer | https://www.worldometers.info/coronav... • COVID-19 vaccine tracker (RAPS) | https://www.raps.org/news-and-article... • Safety and Immunogenicity of Two RNA-Based Covid-19 Vaccine Candidates (NEJM) | https://www.nejm.org/doi/full/10.1056... • A prefusion SARS-CoV-2 spike RNA vaccine is highly immunogenic and prevents lung infection in non-human primates (bioRxiv) | https://www.biorxiv.org/content/10.11... • Pfizer and BioNTech Announce Vaccine Candidate Against COVID-19 Achieved Success in First Interim Analysis from Phase 3 Study (BioNTech) | https://investors.biontech.de/news-re... • Why mRNA represents a disruptive new drug class {BioNTech) | https://biontech.de/how-we-translate/... • • THE MEDCRAM WEBSITE: • Visit us for videos on over 60 medical topics and CME / CEs for medical professionals: https://www.medcram.com/?utm_source=Y... • • SUBSCRIBE TO THE MEDCRAM YOUTUBE CHANNEL: • https://www.youtube.com/user/MEDCRAMv... • Get notified of new videos by hitting the bell icon: • • RECENT PREVIOUS COVID-19 UPDATES: • • Please visit MedCram.com for the full series: • Coronavirus Update 115: Convalescent Plasma vs Monoclonal Antibodies for COVID 19 Treatment    • Coronavirus Update 115: Convalescent ...   • Coronavirus Update 114: COVID 19 Death Rate Drops; NAC (N acetylcysteine) Data    • Coronavirus Update 114: COVID 19 Deat...   • Coronavirus Update 113: Remdesivir May Not Work for COVID 19    • Coronavirus Update 113: Remdesivir Ma...   • Coronavirus Update 112: Linoleic Acid; Vaccines; UK COVID 19 Data    • Coronavirus Update 112: Linoleic Acid...   • Coronavirus Update 111: Masks; New Vitamin D Data and COVID 19; NAC    • Coronavirus Update 111: Masks; New Vi...   • Coronavirus Pandemic Update 110: Trump's Risk Factors and COVID-19 Prognosis; Interferon    • Coronavirus Pandemic Update 110: Trum...   • Coronavirus Pandemic Update 109: New Data From Europe As COVID 19 Infections Rise    • Coronavirus Pandemic Update 109: New ...   • Coronavirus Pandemic Update 108: High Risk COVID 19 Behaviors; Cases Rise in Europe    • Coronavirus Pandemic Update 108: High...   • Coronavirus Pandemic Update 107: Monoclonal Antibodies for COVID 19 Treatment and Prevention?    • Coronavirus Pandemic Update 107: Mono...   • Coronavirus Pandemic Update 105: FDA Authorized Treatments; COVID 19 Vaccine Update    • Coronavirus Pandemic Update 105: FDA ...   • Coronavirus Pandemic Update 103: Convalescent Plasma Treatment the FDA; College Campuses Close    • Coronavirus Pandemic Update 103: Conv...   • All coronavirus updates are at MedCram.com (including monoclonal antibody treatment vs convalescent plasma treatment, COVID vaccine, COVID 19 prevention, Pfizer vaccine, Biontech, coronavirus vaccine, COVID 19 treatments, COVID-19 vaccine updates, and more). • We offer over 60 medical topics (ECG Interpretation, DKA, influenza, measles, mechanical ventilation, etc.) on our website. • • MEDCRAM WORKS WITH MEDICAL PROGRAMS AND HOSPITALS: • MedCram offers group discounts for students and a variety of medical programs, hospitals, and other institutions. Contact us at [email protected] if you are interested. • • MEDIA CONTACT: • Roger Seheult, MD • Board Certified in Internal Medicine, Pulmonary Disease, Critical Care, and Sleep Medicine. • Associate Professor at the University of California, Riverside School of Medicine • Media Contact: [email protected] • Media contact info: https://bit.ly/3q2ErVv • Video Produced by Kyle Allred • FOLLOW US ON SOCIAL MEDIA: •   / medcram   •   / medcramvideos   •   / medcram   • • DISCLAIMER: • MedCram medical videos are for medical education and exam preparation, and NOT intended to replace recommendations from your doctor. • #COVID19 #SARSCoV2

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