How is Agomelatine different from other Antidepressants A Psychiatrist Explains Dr Rege

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Agomelatine, also known as Valdoxan, is a novel and atypical antidepressant that acts as a melatonergic antidepressant and has a distinctly favourable side effect profile. Dr Sanil Rege, Consultant Psychiatrist, explains its mechanism of action. • #agomelatine #valdoxan #antidepressants • Agomelatine is a melatonin receptor agonist (M1 M2) and a serotonin 5 HT2C receptor antagonist with a favourable side effect profile. There is a lack of sexual dysfunction, sleep benefits, and no discontinuation symptoms – all of which confer valuable clinical benefits in the treatment of depression. • Hyperactivity of the 5-HT2C receptors may contribute to the symptoms of MDD, and agomelatine-induced 5-HT2C antagonism has been shown to increase the release of dopamine and norepinephrine in the frontal cortex. • Agomelatine is evidence-based in the treatment of depression, anxiety, OCD and bipolar depression. • Read more on agomelatine: https://psychscenehub.com/psychinsigh... • Music : • Music by : • Song: Clarx - Shakedown [NCS Release] • Music provided by NoCopyrightSounds • Free Download/Stream: http://ncs.io/Shakedown • Watch: • Clarx - Shakedown | Future House | NC...

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