Oxygen As A Leaving Group Using Tosylate And Mesylate in Substitution and Elimination Reactions

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https://Leah4sci.com/elimination presents: Understanding the Effects of Leaving Groups in substitution elimination reactions (Part 2) - Turning a bad leaving group like OH into a good leaving group through protonation, or using Tosylate and Mesylate • 📺Watch Next: SN1 Reaction Rate and Mechanism • SN1 Reaction Rate and Mechanism - Uni... • Need help with Orgo? Download my free guide ’10 Secrets to Acing Organic Chemistry’ HERE: https://leah4sci.com/orgo-ebook/ • In this video you’ll learn how to turn a bad leaving group like oxygen into a good leaving group. • We’ll review why oxygen is a bad leaving group, then look at ‘bribing’ via protonation, or adding a bulkier group like a tosylate as tosyl chloride, or mesylate as mesyl chloride. • ↪ Links Resources Mentioned In This Video ↩ • ▸Substitution and Elimination Reactions Series + Cheat Sheet https://Leah4sci.com/elimination • ▸Formal Charge Formula and Shortcut https://Leah4sci.com/formal • ▸Resonance Structures in Organic Chemistry Series https://Leah4sci.com/resonance • - - - - - - - - - - - - - - - - - - - - - - - • ⏱ In this video: • [0:24] Why Oxygen is a Bad Leaving Group • [1:08] Bribing the Oxygen by Protonation • [2:24] Structures for the Sulfonyl Chlorides • [2:57] How Oxygen Attacks the Sulfonyl Chloride • [3:30] A Simplified Mechanism for Using Tosylate • - - - - - - - - - - - - - - - - - - - - - - - • Follow along with your semester by using my Orgo Syllabus Companion: https://leah4sci.com/syllabus • For more in-depth review including practice problems and explanations, come join my online membership site, the Organic Chemistry Study Hall: https://leah4sci.com/join • ❓Questions? Ask me here: https://Leah4sci.com/contact • 👩‍🏫 For private online tutoring visit my website: https://leah4sci.com/organic-chemistry • Let’s connect:▸Instagram: / leah4sci • ▸Facebook: / leah4sci • ▸Twitter: / leah4sci • ▸Pinterest: / leah4sci • 🔔 Subscribe to my channel so you don’t miss out on any new videos 🔔 • https://leah4sci.com/youtube • 🩺💉 My MCAT YouTube Channel: https://leah4sci.com/MCATyoutube 💉🩺

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