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Mitochondria Dysfunction Whats ACTUALLY Happening
>> YOUR LINK HERE: ___ http://youtube.com/watch?v=c4JsEBI9u6I
📌 𝐅𝐨𝐥𝐥𝐨𝐰 𝐨𝐧 𝐈𝐧𝐬𝐭𝐚𝐠𝐫𝐚𝐦:- / drgbhanuprakash • 📌𝗝𝗼𝗶𝗻 𝗢𝘂𝗿 𝗧𝗲𝗹𝗲𝗴𝗿𝗮𝗺 𝗖𝗵𝗮𝗻𝗻𝗲𝗹 𝗛𝗲𝗿𝗲:- https://t.me/bhanuprakashdr • 📌𝗦𝘂𝗯𝘀𝗰𝗿𝗶𝗯𝗲 𝗧𝗼 𝗠𝘆 𝗠𝗮𝗶𝗹𝗶𝗻𝗴 𝗟𝗶𝘀𝘁:- https://linktr.ee/DrGBhanuprakash • Introduction • -------------------- • Mitochondria are often described as the powerhouses of the cell because of their central role in the synthesis of ATP, a vital source of energy for the body. They are composed of a double membrane, intramembranous space, and matrix. Various mitochondrial types can be differentiated based on the inner membrane structure. • Structure • --------------- • The structure and DNA of mitochondria resemble the structure and DNA of prokaryotes. Mitochondria are believed to have been prokaryotes originally that evolved into endosymbionts living inside eukaryotes • Mitochondrial membrane • ----------------------------------------- • There are two, highly specialized mitochondrial membranes that surround the mitochondrion. They provide the framework for the electron transport chain and ATP production. • Outer membrane • --------------------------- • Structure: smooth • Permeability: interspersed with pores, highly permeable for various molecules • Inner membrane • --------------------------- • Structure: convoluted • Permeability: impermeable, especially to ions; however the inner membrane contains many different highly specific transport proteins • Characteristic component: cardiolipin (stabilizes the enzymes of oxidative phosphorylation) • Mitochondrial matrix • ---------------------------------- • Contains mitochondrial DNA (mtDNA) and ribosomes responsible for the synthesis of ∼ 15% of the mitochondrial proteins • The remaining mitochondrial proteins are encoded in the nucleus and are transported into the mitochondria in an unfolded state, where they take on their final folded structure. • Functions • ----------------- • Energy production: The inner mitochondrial membrane contains the enzymes of the respiratory chain and the ATP synthase that together produce ATP (oxidative phosphorylation). • Other metabolic pathways in the matrix • Citric acid cycle • Beta-oxidation • Ketogenesis • Urea cycle • Pyruvate decarboxylation • Heme synthesis • Initiation of apoptosis • #mitochondria #bichemvideos #usmlevideos #structureofmitochondria #usmlestep1videos #animatedmedicalvideos #biochemanimatedvideos #drgbhanuprakash #mbbs #neetpg #fmge
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