Understanding HIV and its treatment











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Millions of people live with HIV, a disease that weakens the body’s defense against ordinary infections. • • The body’s defense is the immune system, made up of white blood cells, antibodies and other cells. • • CD4, a type of white blood cell, fights off invaders. But HIV attacks CD4 cells. • • The HIV life cycle begins when HIV attaches itself to the CD4 cell and transfers its proteins and genetic material into it. • • Next, an HIV enzyme called Reverse Transcriptase converts HIV RNA into HIV DNA while an Integrase Enzyme integrates HIV DNA into the host CD4 cell’s DNA. • • Then, the Protease enzyme processes the produced HIV material for assembly into an immature virus. • • Finally, mature HIV materials are released into the body, where the cycle starts over again. • • There is no cure for HIV. But anti-retroviral medication, or ARVs, reduce HIV reproduction by interrupting the HIV life cycle. • • Entry Inhibitors prevent HIV material from entering CD4 cells while Reverse Transcriptase Inhibitors stop the reverse transcriptase enzymes from converting HIV RNA into HIV DNA. • • Later, Integrase Inhibitors block HIV integrase enzyme from integrating HIV DNA into CD4 DNA, while Protease Inhibitors block the protease enzymes from enabling the production of new HIV material. • • By learning more about HIV and ARVs, you are better able to adhere to HIV treatment and protect others from getting infected! • English    • Understanding HIV and its treatment   • Portuguese    • Compreendendo o HIV e seu tratamento   • French    • Comprendre le VIH et son traitement   • Spanish    • Comprensión del VIH y su tratamiento   • • Subscribe to ITPC: https://www.youtube.com/channel/UC43K... • • Latest COVID-19 resources: https://itpcglobal.org/covid-19/ • • For more resources from ITPC, go to our official website at https://itpcglobal.org/resources/ • • Join the Fight! https://itpcglobal.org/join-the-fight/

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