16 Recombinant DNA Cloning amp Editing











>> YOUR LINK HERE: ___ http://youtube.com/watch?v=cbgDoMTFqxE

A series of short presentations on gene editing is brought to you by Dr Adam West, College of Medical Veterinary and Life Sciences at the University of Glasgow, Scotland. • https://www.gla.ac.uk/people/adamwest • This introduction covers cellular DNA repair pathways and the possible genome editing outcomes when using sequence-specific nucleases. • This is part of a series (   • Genome Editing Explained  ) that also covers • Zinc finger nucleases (ZFNs) • Transcription activator-like effector nucleases (TALENs) • CRISPR adaptive immune systems • Using CRISPR/Cas9 for genome editing • CRISPR specificity • Precision editing • Homology directed repair • Prime editing • This presentation is primarily aimed at university students, researchers, clinicians and journalists interested in fields related to molecular biology and genetics. It is for education purposes only. • Please leave a comment to let us know whether this was helpful to you and what you think we should cover next. We are a new channel so please give us a like and share our video on your social media if you think others should see it. We have a lot of content coming up, so please subscribe! • More accessible presentations for a wide audience can be found in the “Explained Simply” section of this channel in the near future. • Artwork is © Adam West with the exception of images and data taken from publications referenced in these slides. References to reviews and journal articles are denoted by circled numbers at the bottom right of the slides. Links to these numbered articles are listed below. We recommend these as your best way to begin further reading on this subject. • Publication List • 3. Ceccaldi R, Rondinelli B, D'Andrea AD. • Repair Pathway Choices and Consequences at the Double-Strand Break. • Trends Cell Biol. 2016 Jan;26(1):52-64. • https://doi.org/10.1016/j.tcb.2015.07... • Music credits • “Go, Icarus! Go!” by The Whole Other • “New Year” by Bad Snacks • (YouTube Audio Library)

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