T helper 1 lymphocytes











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T helper lymphocytes (Th) are arguably the most important cells in specific immunity, because they activate, regulate and direct the immune response. Naïve T helper cells recognize antigens presented in association to MHC II molecules by APCs; depending on the type of APC, on the initial innate immune response and on the type of cytokines present in the microenvironment, Th can differentiate into different subsets of lymphocytes (Th1, Th2, Th17, Th9, Th22 and Treg) which can promote the development of different types of immune response according to their production of a different cytokine pattern. Th1 are responsible of cell-mediated immunity against intracellular pathogens. https://www.pig333.com/immunology/the...

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