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Medical Cannabis for Epilepsy and Seizures
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Medical Cannabis for Epilepsy and Seizures • https://www.dubermedical.com/best-can... • Cannabis has a historical association with the management of seizures, dating back to ancient times [3]. Within cannabis, two key cannabinoids, delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD), play significant roles. In the realm of epilepsy and seizure management, CBD takes the forefront as the primary cannabinoid of interest. • Physicians employ CBD in various ways, either as a complement to pharmaceutical treatments or as a standalone approach when tending to individuals with epilepsy [2]. However, CBD has garnered particular attention in the context of Dravet syndrome. This form of epilepsy is characterized by its resistance to conventional medications, yet it has displayed encouraging responses to CBD therapy. • CBD has also earned widespread recognition because nearly one-third of epilepsy patients do not experience favorable outcomes with pharmaceutical interventions [3]. Moreover, the undesirable and often disruptive side effects associated with anticonvulsant drugs have propelled the exploration of CBD as an alternative solution for epilepsy management. • Medical Cannabis for Epilepsy and Seizure Disorders • Although the precise mechanism by which CBD reduces seizures in humans remains elusive, CBD exhibits an affinity for multiple types of receptors in the body due to the wide reach of the endocannabinoid system [2]. CBD’s interaction with these receptors results in the functional adjustment of neuronal excitability, a phenomenon relevant to the pathology of epilepsy. The biological targets of CBD in epilepsy are thought to be transient receptor potential vanilloid-1 (TRPV1), the orphan G protein-coupled receptor-55 (GPR55), and the equilibrative nucleoside transporter 1 (ENT-1). • Since THC is not beneficial for the treatment of epilepsy and seizure disorders and is not appropriate for use by children and teens, Epidiolex may be the most appropriate medical marijuana option. Epidiolex is a prescription medication that contains cannabidiol (CBD) as its active ingredient [1]. It is the first and only FDA-approved cannabis-derived drug in the United States. Epidiolex is specifically used to treat Lennox-Gastaut syndrome and Dravet syndrome. It is available in an oral solution form and is administered under the supervision of a healthcare provider. • Epidiolex is different from most other CBD products available in the market because it is subject to strict regulations and quality control standards [1]. It has undergone extensive clinical testing to prove its safety and efficacy for the treatment of these specific forms of epilepsy. It was approved by the U.S. Food and Drug Administration (FDA) in 2018 and is available by prescription from a healthcare provider. • Best Cannabis Strains for Epilepsy and Seizure • Aside from the option of Epidiolex, your medical marijuana doctor may deem it appropriate for you to use cannabis. If that is the case, you will want to look for strains that are high in CBD and very low in THC. These strains are more appropriately called hemp flower since the term marijuana implies a significant THC content. With that in mind, here are some high CBD strains to consider. • Click the link above to learn more about the strains we recommend. • #epilepsy #cbdforpain #seizures
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