Youtor
>> YOUR LINK HERE: ___ http://youtube.com/watch?v=gtwK7wcU5Sk
๐ ๐ ๐จ๐ฅ๐ฅ๐จ๐ฐ ๐จ๐ง ๐๐ง๐ฌ๐ญ๐๐ ๐ซ๐๐ฆ:- / drgbhanuprakash • ๐๐๐ผ๐ถ๐ป ๐ข๐๐ฟ ๐ง๐ฒ๐น๐ฒ๐ด๐ฟ๐ฎ๐บ ๐๐ต๐ฎ๐ป๐ป๐ฒ๐น ๐๐ฒ๐ฟ๐ฒ:- https://t.me/bhanuprakashdr • ๐๐ฆ๐๐ฏ๐๐ฐ๐ฟ๐ถ๐ฏ๐ฒ ๐ง๐ผ ๐ ๐ ๐ ๐ฎ๐ถ๐น๐ถ๐ป๐ด ๐๐ถ๐๐:- https://linktr.ee/DrGBhanuprakash • Vitamin D (calciferol): Sources, Synthesis, Metabolism, Functions, RDA, Regulation and Deficiency • Vitamin D (calciferol) • Characteristics • ------------------------- • Active form: 1,25-dihydroxyvitamin D (1,25-(OH)2 D3, calcitriol) • Sources: • -------------- • Ergocalciferol (vitamin D2): mushrooms, fortified foods (e.g., milk, breakfast cereals, formula), yeast (from ergosterol) • Cholecalciferol (vitamin D3) • Synthesized in the skin (stratum basale) when exposed to UV light • Fortified foods (e.g., milk, breakfast cereals, formula), fatty fish (liver), egg yolks • Vitamin D synthesis • -------------------------------- • Liver: cholesterol → 7-dehydrocholesterol (provitamin D3) • Enzyme: cholesterol dehydrogenase • Skin • Storage of 7-dehydrocholesterol • Cleavage of 7-dehydrocholesterol via irradiation with UV light → cholecalciferol (in the stratum basale of the skin) • Liver: hydroxylation of cholecalciferol to 25-hydroxyvitamin D (25-OH D3, calcidiol; activated vitamin D2) • Kidneys: 1α-hydroxylase hydroxylates 25-hydroxyvitamin D → 1,25-dihydroxyvitamin D • Transport to target cells: vitamin D-binding protein (DBP) • Storage: mainly in adipose tissue as 25-hydroxycholecalciferol • Regulation of vitamin D synthesis: via regulation of 1α-hydroxylase activity in proximal convoluted tubule • ↓ Calcium, ↓ phosphate, and ↑ PTH → ↑ 1α-hydroxylase activity → ↑ 1,25-dihydroxyvitamin D biosynthesis • ↑ Calcium, ↑ phosphate, and ↑ 1,25-dihydroxyvitamin D → ↓ 1α-hydroxylase activity → ↓ 1,25-dihydroxyvitamin D biosynthesis • #vitamind #vitamindbiochemistry #vitamindsources #vitamindbenefits #vitamindsynthesis #vitamindfunctions #vitamindfoods #vitaminddosage #vitaminDrichfoods #vitamindfoods #vitaminDbiology #vitamindmetabolism #vitaminDusmle #vitamindvideo #vitamindlecture #vitamindanimation
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