Removing senescent cells bad











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Senescent cells accumulate with age. Studies have shown that removing senescent cells can alleviate symptoms of aging. However, a recent study has put this into question... • References; • Grosse et al., Defined p16High Senescent Cell Types Are Indispensable for Mouse Healthspan, Cell Metabolism • (2020), https://doi.org/10.1016/j.cmet.2020.0... • Xu, M., Pirtskhalava, T., Farr, J.N. et al. Senolytics improve physical function and increase lifespan in old age. Nat Med 24, 1246–1256 (2018). https://doi.org/10.1038/s41591-018-00... • Baker, D., Wijshake, T., Tchkonia, T. et al. Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders. Nature 479, 232–236 (2011). https://doi.org/10.1038/nature10600 • Icons in intro; https://www.freepik.com/free-photos-v... Background vector created by freepik - www.freepik.com

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