Mowei Zhou Understanding the Heterogeneity of Plant Proteoforms by Top Down Mass Spectrometry

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0:00 Intro • 3:38 Mowei Zhou • 51:52 Q A • Plants have large genomes and a repertoire of diverse proteoforms, including many with unknown functions. Mowewi will discuss a top-down proteomics (TDP) study of soybean nodules that revealed interesting patterns of truncated proteoforms and unexpected modifications. In addition, he will discuss a side story behind a recently published de novo sequencing study of purified Forsythia plant cell wall proteins and highlight the potential of TDP for proteoform discovery.

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