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Physiology of Ghrelin Animation USMLE Step 1
>> YOUR LINK HERE: ___ http://youtube.com/watch?v=hmH423aeRYA
📌 𝐅𝐨𝐥𝐥𝐨𝐰 𝐨𝐧 𝐈𝐧𝐬𝐭𝐚𝐠𝐫𝐚𝐦:- / drgbhanuprakash • 📌𝗝𝗼𝗶𝗻 𝗢𝘂𝗿 𝗧𝗲𝗹𝗲𝗴𝗿𝗮𝗺 𝗖𝗵𝗮𝗻𝗻𝗲𝗹 𝗛𝗲𝗿𝗲:- https://t.me/bhanuprakashdr • 📌𝗦𝘂𝗯𝘀𝗰𝗿𝗶𝗯𝗲 𝗧𝗼 𝗠𝘆 𝗠𝗮𝗶𝗹𝗶𝗻𝗴 𝗟𝗶𝘀𝘁:- https://linktr.ee/DrGBhanuprakash • Physiology of Ghrelin Animation: USMLE Step 1 • Ghrelin is a hormone primarily produced by the stomach, although it is also synthesized in smaller amounts by other tissues, such as the small intestine, pancreas, and brain. It plays a crucial role in regulating appetite and energy balance in the body. Here's an overview of the physiology of ghrelin: • Production: Ghrelin is synthesized and secreted mainly by the endocrine cells in the lining of the stomach called X/A-like cells (also known as ghrelin cells). These cells release ghrelin into the bloodstream in response to certain stimuli, including an empty stomach, low blood glucose levels, and sleep deprivation. • Appetite Regulation: Ghrelin acts as an orexigenic hormone, meaning it stimulates appetite and food intake. When the stomach is empty, ghrelin levels rise, sending signals to the hypothalamus in the brain to increase hunger and promote feeding behavior. Ghrelin acts on specific receptors in the hypothalamus, particularly the arcuate nucleus, which plays a crucial role in regulating food intake. • Growth Hormone Release: Ghrelin also influences the release of growth hormone (GH) from the pituitary gland. It stimulates GH secretion, particularly during periods of fasting or calorie restriction. GH has various effects on metabolism, growth, and body composition. • Metabolic Effects: Ghrelin has several metabolic effects that go beyond its appetite-stimulating properties. It can increase gastric motility and acid secretion, which prepares the stomach for food digestion. Ghrelin also affects glucose metabolism, promoting gluconeogenesis (production of glucose from non-carbohydrate sources) and insulin release. Moreover, ghrelin can influence lipid metabolism and fat storage. • Feedback Mechanisms: Once food is consumed, ghrelin levels decrease rapidly. The release of other hormones, such as insulin and peptide YY (PYY), in response to food intake, contributes to the suppression of ghrelin production. Leptin, a hormone produced by fat cells, also acts on the hypothalamus to inhibit ghrelin release, providing further feedback for appetite regulation. • Other Functions: Apart from its role in appetite regulation, ghrelin has been implicated in various physiological processes. It has effects on reward-seeking behavior, mood regulation, sleep, cardiovascular function, and immune response. Research is ongoing to understand the full range of ghrelin's functions in the body. • #GhrelinPhysiology #AppetiteRegulation #HungerHormone #Metabolism #FoodIntake #HormonalBalance #GrowthHormone #EnergyBalance #Nutrition #HormoneRegulation #DigestiveSystem #HungerSignals #BodyWeight #EndocrineSystem #GutHormones #HormonalControl #GhrelinFunction #HormonalFeedback #HungerAndSatiety #EatingBehavior #fmge #fmgevideos #rapidrevisionfmge #fmgejan2023 #mbbslectures #nationalexitexam #nationalexittest #neetpg #usmlepreparation #usmlestep1 #fmge #usmle #drgbhanuprakash #medicalstudents #medicalstudent #medicalcollege #neetpg2023 #usmleprep #usmlevideos #usmlestep1videos #medicalstudents #neetpgvideos
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