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http://youtube.com/watch?v=hqkTjzGh7_M

00:00 Review • 04:10 Learning Outcomes • 06:07 Mutations - categories • 07:20 Point mutations: UV light as a cause • 12:52 Point mutations: Benzo[a]pyrene • 16:17 Effects of various types of mutations • 18:15 Rating synonymous/nonsynonymous (silent, missense, nonsense) mutations and their effect on protein sequence; ability to be acted on by natural selection • 23:48 Effects of indel mutations • 24:41 One mechanism that can cause indel mutations • 27:40 Predicting how indels will impact protein length • 29:00 Exercise: designing mutations that have specific effects on a protein sequence • 37:00 Transposons • 40:45 Summary • 41:25 Are mutations random? Google Classroom PDF annotation exercise (and practicing this workflow in preparation for the midterm exam)

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