Youtor
MiniLecture Series HIV Capsid Inhibitors Mechanism of Action
>> YOUR LINK HERE: ___ http://youtube.com/watch?v=iZ9KDxV5Zbs
Dr. David Spach discusses HIV capsid inhibitors, a new antiviral medication class. Using unique illustrations, he first reviews basic concepts related to the normal structure and function of the HIV capsid before exploring the highly unique multistage mechanism of action that includes inhibition of capsid nuclear import, inhibition of capsid uncoating, and inhibition of capsid assembly. He also talks about the initiation and maintenance dosing of lenacapavir – the first and only FDA-approved capsid inhibitor as of July 2024. • 0:00 Intro • 0:22 HIV Antiretroviral Therapy • 0:44 HIV Capsid Structure and Function • 3:42 Lenacapavir and Capsid Binding • 5:34 Mechanism of Action of HIV Capsid Inhibitors • 13:12 Lenacapavir • 16:22 Summary
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