Food constituent–drug interactions Influence of quantitative modelling on drug labelling

>> YOUR LINK HERE: ___ http://youtube.com/watch?v=lYDfEkL6z9Y

Topics covered: • o Development of a PBPK model for bergamottin, a grapefruit juice component, as a perpetrator. • o Food-constituent-drug interaction (FC-DI) for bergamottin, hyperforin, and curcumin with existing (Simcyp) victim compounds and prospective effects on oncology drug PK. •  Interplay between inhibition and induction. • o Discuss further mechanisms of FC-DI for consideration and methods of application. • Certara accelerates medicines to patients using proprietary biosimulation software and technology to transform traditional drug discovery and development. Its clients include 1,600 global biopharmaceutical companies, leading academic institutions, and key regulatory agencies across 60 countries. • Please visit us at https://www.certara.com/

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